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Phase II study of erlotinib in elderly patients with non-small cell lung cancer harboring epidermal growth factor receptor mutations.

Cancer chemotherapy and pharmacology - 1 Jul 2015

Inoue Yusuke, Inui Naoki, Asada Kazuhiro, Karayama Masato, Matsuda Hiroyuki, Yokomura Koshi, Koshimizu Naoki, Imokawa Shiro, Yamada Takashi, Shirai Toshihiro, Kasamatsu Norio, Suda Takafumi

Abstract excerpt

PURPOSE: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors are key drugs in the treatment of non-small cell lung cancer (NSCLC) harboring EGFR activating mutations. We assessed the efficacy and safety of one EGFR tyrosine kinase inhibitor, erlotinib, in elderly Japanese patients with EGFR-mutated NSCLC. METHODS: Elderly patients aged 75 or older with advanced or recurrent NSCLC and EGFR mutations...

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PMID: 26003540
DOI: 10.1007/s00280-015-2784-x

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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