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Article

Resistance gene pool to co-trimoxazole in non-susceptible Nocardia strains

28 Apr 2015

Abstract excerpt

The soil-borne pathogen Nocardia sp. causes severe cutaneous, pulmonary, and central nervous system infections. Against them, co-trimoxazole (SXT) constitutes the mainstay of antimicrobial therapy. However, some Nocardia strains show resistance to SXT, but the underlying genetic basis is unknown. We investigated the presence of genetic resistance determinants and class 1-3 integrons in 76 SXT-resistant Nocardia...

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PMID: 25972856
DOI: 10.3389/fmicb.2015.00376

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