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Article

Assessment of the predictive accuracy of five in silico prediction tools, alone or in combination, and two metaservers to classify long QT syndrome gene mutations.

BMC medical genetics - 13 May 2015

Leong Ivone U S, Stuckey Alexander, Lai Daniel, Skinner Jonathan R, Love Donald R

Abstract excerpt

BACKGROUND: Long QT syndrome (LQTS) is an autosomal dominant condition predisposing to sudden death from malignant arrhythmia. Genetic testing identifies many missense single nucleotide variants of uncertain pathogenicity. Establishing genetic pathogenicity is an essential prerequisite to family...

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Source

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Identifiers

PMID: 25967940
DOI: 10.1186/s12881-015-0176-z
PMCID: PMC4630850

Genes

MCC
KCNH2
KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25967940-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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