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Article

Vaccinology in the era of high-throughput biology.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 19 Jun 2015

Nakaya Helder I, Pulendran Bali

Abstract excerpt

Vaccination has been tremendously successful saving lives and preventing infections. However, the development of vaccines against global pandemics such as HIV, malaria and tuberculosis has been obstructed by several challenges. A major challenge is the lack of knowledge about the correlates and mechanisms of protective immunity. Recent advances in the application of systems biological approaches to analyse immune...

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Identifiers

PMID: 25964458
DOI: 10.1098/rstb.2014.0146
PMCID: PMC4527391

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