Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hereditary leukoencephalopathy with axonal spheroids: a spectrum of phenotypes from CNS vasculitis to parkinsonism in an adult onset leukodystrophy series.

Journal of neurology, neurosurgery, and psychiatry - 1 May 2016

Lynch David S, Jaunmuktane Zane, Sheerin Una-Marie, Phadke Rahul, Brandner Sebastian, Milonas Ionnis, Dean Andrew, Bajaj Nin, McNicholas Nuala, Costello Daniel, Cronin Simon, McGuigan Chris, Rossor Martin, Fox Nick, Murphy Elaine, Chataway Jeremy, Houlden Henry

Abstract excerpt

BACKGROUND: Hereditary diffuse leukoencephalopathy with neuroaxonal spheroids (HDLS) is a hereditary, adult onset leukodystrophy which is characterised by the presence of axonal loss, axonal spheroids and variably present pigmented macrophages on pathological examination. It most frequently prese...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axons
Share to Hereditary Central Nervous System Demyelinating Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukoencephalopathies

Share to Mutation

Share to Parkinsonian Disorders

Share to Phenotype

Share to Receptors, Colony-Stimulating Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 25935893
DOI: 10.1136/jnnp-2015-310788
PMCID: PMC4853550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25935893-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hereditary leukoencephalopathy with axonal spheroids: a spectrum of phenotypes from CNS vasculitis to parkinsonism in an adult onset leukodystrophy series.PMID 25935893Read ↗

Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia Caused by a Novel R782G Mutation in CSF1R.Semantic proximity Read ↗

Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS): update on molecular genetics.Semantic proximity Read ↗

Enlarging the nosological spectrum of hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS).Semantic proximity Read ↗

De novo mutations in hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS).Semantic proximity Read ↗

Hereditary diffuse leukoencephalopathy with spheroids with phenotype of primary progressive multiple sclerosis.Semantic proximity Read ↗

Clinical features and genetic characteristics of hereditary diffuse leukoencephalopathy with spheroids due to CSF1R mutation: a case report and literature reviewSemantic proximity Read ↗

Genetic analysis of inherited leukodystrophies: genotype-phenotype correlations in the CSF1R gene.Semantic proximity Read ↗

A family with hereditary diffuse leukoencephalopathy with spheroids caused by a novel c.2442+2T>C mutation in the CSF1R gene.Semantic proximity Read ↗

A Novel CSF1R Mutation in a Patient with Clinical and Neuroradiological Features of Hereditary Diffuse Leukoencephalopathy with Axonal Spheroids.Semantic proximity Read ↗

Adult-onset leukoencephalopathy with neuroaxonal spheroids and pigmented glia: report of five cases and a new mutation.Semantic proximity Read ↗

Clinical and genetic characterization of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia associated with CSF1R mutation.Semantic proximity Read ↗

A novel A781V mutation in the CSF1R gene causes hereditary diffuse leucoencephalopathy with axonal spheroids.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.