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Article

miR-144/451 Promote Cell Proliferation via Targeting PTEN/AKT Pathway in Insulinomas

28 Apr 2015

Abstract excerpt

Insulinoma is the main type of functional pancreatic neuroendocrine tumors. The functional microRNAs (miRNAs) regulating tumor growth and progression in insulinomas are still unknown. We conducted the miRNA expression profile analysis using miRNA quantitative RT-PCR array and identified 114 differentially expressed miRNAs in human insulinomas compared with normal pancreatic islets. Forty-one differentially...

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PMID: 25919186
DOI: 10.1210/en.2014-1966

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