Article
An Ixodes scapularis cell line with a predominantly neuron-like phenotype.
Experimental & applied acarology - 1 Jul 2015
Oliver Jonathan D, Chávez Adela S Oliva, Felsheim Roderick F, Kurtti Timothy J, Munderloh Ulrike G
Abstract excerpt
The Ixodes scapularis embryo-derived cell line ISE6 is the most widely utilized tick-derived cell line due to its susceptibility to a wide variety of tick- and non-tick-vectored pathogens. Little is known about its tissue origin or biological background. Protein expression of ISE6 cells was compared with that of another I. scapularis-derived cell line, IDE12, and dissected tick synganglia. Results demonstrated...
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