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Insights into the evolutionary history of Japanese encephalitis virus (JEV) based on whole-genome sequences comprising the five genotypes.

Virology journal - 14 Mar 2015

Gao Xiaoyan, Liu Hong, Li Minghua, Fu Shihong, Liang Guodong

Abstract excerpt

BACKGROUND: Japanese encephalitis virus (JEV) is the etiological agent of Japanese encephalitis (JE), one of the most serious viral encephalitis worldwide. Five genotypes have been classified based on phylogenetic analysis of the viral envelope gene or the complete genome. Previous studies based on four genotypes have reported that in evolutionary terms, genotype 1 JEV is the most recent lineage. However, until...

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PMID: 25884184
DOI: 10.1186/s12985-015-0270-z
PMCID: PMC4369081

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