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Article

SERPINB11 frameshift variant associated with novel hoof specific phenotype in Connemara ponies.

PLoS genetics - 1 Apr 2015

Finno Carrie J, Stevens Carlynn, Young Amy, Affolter Verena, Joshi Nikhil A, Ramsay Sheila, Bannasch Danika L

Abstract excerpt

Horses belong to the order Perissodactyla and bear the majority of their weight on their third toe; therefore, tremendous force is applied to each hoof. An inherited disease characterized by a phenotype restricted to the dorsal hoof wall was identified in the Connemara pony. Hoof wall separation disease (HWSD) manifests clinically as separation of the dorsal hoof wall along the weight-bearing surface of the hoof...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25875171
DOI: 10.1371/journal.pgen.1005122
PMCID: PMC4395385

Genes

SERPINB11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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