Article
A novel frameshift MSX1 mutation in a Saudi family with autosomal dominant premolar and third molar agenesis.
Archives of oral biology - 1 Jul 2015
AlFawaz Shurog, Plagnol Vincent, Wong Ferranti S L, Kelsell David P
Abstract excerpt
OBJECTIVES: In this study, the aim was to investigate a consanguineous Saudi family with non-syndromic premolars and third molars agenesis and to identify the causal mutation(s) using whole exome sequencing. DESIGN: Family phenotype and family pedigree were constructed from clinical and radiographic examinations. Whole exome sequencing was performed in two affected members of the Saudi family using the SureSelect...
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