Article
Superiority of [68Ga]-DOTATATE PET/CT to Other Functional Imaging Modalities in the Localization of SDHB-Associated Metastatic Pheochromocytoma and Paraganglioma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2015
Janssen Ingo, Blanchet Elise M, Adams Karen, Chen Clara C, Millo Corina M, Herscovitch Peter, Taieb David, Kebebew Electron, Lehnert Hendrik, Fojo Antonio T, Pacak Karel
Abstract excerpt
PURPOSE: Patients with succinate dehydrogenase subunit B(SDHB) mutation-related pheochromocytoma/paraganglioma (PHEO/PGL) are at a higher risk for metastatic disease than other hereditary PHEOs/PGLs. Current therapeutic approaches are limited, but the best outcomes are based on the early and proper detection of as many lesions as possible. Because PHEOs/PGLs overexpress somatostatin receptor 2 (SSTR2), the goal...
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