Article
Exosome-like vesicles derived by Schistosoma japonicum adult worms mediates M1 type immune- activity of macrophage.
Parasitology research - 1 May 2015
Wang Lifu, Li Zhitao, Shen Jia, Liu Zhen, Liang Jinyi, Wu Xiaoying, Sun Xi, Wu Zhongdao
Abstract excerpt
Exosomes are 30-100-nm membrane vesicles of endocytic origin that are released into the extracellular space upon fusion of the multi-vesicular bodies (MVB) with the plasma membrane, while initial studies described that the role of exosomes was a reticulocyte cargo-disposal mechanism allowing remodeling of the plasma membrane during the maturation of reticulocytes to erythrocytes. Recent studies indicate that...
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