Article
Deep phylogenetic analysis of haplogroup G1 provides estimates of SNP and STR mutation rates on the human Y-chromosome and reveals migrations of Iranic speakers.
PloS one - 1 Jan 2015
Balanovsky Oleg, Zhabagin Maxat, Agdzhoyan Anastasiya, Chukhryaeva Marina, Zaporozhchenko Valery, Utevska Olga, Highnam Gareth, Sabitov Zhaxylyk, Greenspan Elliott, Dibirova Khadizhat, Skhalyakho Roza, Kuznetsova Marina, Koshel Sergey, Yusupov Yuldash, Nymadawa Pagbajabyn, Zhumadilov Zhaxybay, Pocheshkhova Elvira, Haber Marc, Zalloua Pierre A, Yepiskoposyan Levon, Dybo Anna, Tyler-Smith Chris, Balanovska Elena
Abstract excerpt
Y-chromosomal haplogroup G1 is a minor component of the overall gene pool of South-West and Central Asia but reaches up to 80% frequency in some populations scattered within this area. We have genotyped the G1-defining marker M285 in 27 Eurasian populations (n= 5,346), analyzed 367 M285-positive samples using 17 Y-STRs, and sequenced ~11 Mb of the Y-chromosome in 20 of these samples to an average coverage of 67X....
Topics
- Chromosomes, Human, Y
- Gene Frequency
- Haplotypes
- Human Migration
- Humans
- Iran
- Language
- Microsatellite Repeats