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Article

Two Case Reports of Successful Treatment of Cholestasis With Steroids in Patients With PFIC-2.

Pediatrics - 1 May 2015

Engelmann Guido, Wenning Daniel, Herebian Diran, Sander Oliver, Dröge Carola, Kluge Stefanie, Kubitz Ralf

Abstract excerpt

Mutations in the gene encoding the canalicular bile salt export pump (BSEP) can result in progressive familial intrahepatic cholestasis type 2 (PFIC-2). Treatment options are limited, and PFIC-2 often necessitates liver transplantation. We report on a young woman and a boy who clinically presente...

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Source

Identifiers

PMID: 25847799
DOI: 10.1542/peds.2014-2376

Genes

ABCB11

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25847799-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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