Article
Childhood asthma and spirometric indices are associated with polymorphic markers of two vitamin D 25-hydroxylase genes.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Jun 2015
Leung Ting Fan, Wang Susan Shuxin, Tang Man Fung, Kong Alice Pik-Shan, Sy Hing Yee, Hon Kam Lun, Chan Juliana Chung-ngor, Wong Gary Wing-kin
Abstract excerpt
BACKGROUND: Polymorphic markers of vitamin D pathway genes have been associated with asthma traits in different White populations. This study investigated the relationship between asthma phenotypes and single nucleotide polymorphisms (SNPs) of vitamin D receptor (VDR), vitamin D binding protein (GC), two 25-hydroxylases (CYP2R1 and CYP27A1), and 1α-hydroxylase (CYP27B1) in Hong Kong Chinese children. METHODS: 23...
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