Article
Pharmacoepidemiology and thalidomide embryopathy surveillance in Brazil.
Reproductive toxicology (Elmsford, N.Y.) - 1 Jun 2015
Sales Luiz Vianna Fernanda, de Oliveira Marcelo Zagonel, Sanseverino Maria Teresa Vieira, Morelo Elaine Faria, de Lyra Rabello Neto Dacio, Lopez-Camelo Jorge, Camey Suzi Alves, Schuler-Faccini Lavinia
Abstract excerpt
INTRODUCTION: Thalidomide causes congenital defects in children, such as limb reduction defects. Currently, it is used for a few indications; in Brazil, where leprosy is endemic, thalidomide is used for the treatment of erythema nodosum leprosum, and recent cases of thalidomide embryopathy have been reported. METHODS: We analyzed the frequency of births with phenotypes consistent with thalidomide embryopathy...
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