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Article

Refractory leg ulcers associated with Klinefelter syndrome.

Journal of Nippon Medical School = Nippon Ika Daigaku zasshi - 1 Jan 2015

Yabuno Yuto, Tosa Mamiko, Iwakiri Itaru, Nomoto Shunichi, Kaneko Mayuko, Kuwahara Kousuke, Hyakusoku Hiko, Murakami Masahiro

Abstract excerpt

We present a man with refractory leg ulcers, bilateral varicosis of the lower extremities, and Buerger disease. Autoimmune work-up was negative. However, chromosome analysis showed Klinefelter syndrome (48 XXY). Ulcerative lesions of the lower extremities are a complication of Klinefelter syndrome. To date, the pathogenesis of ulcers in Klinefelter syndrome has not been clarified, but several factors, such as...

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Identifiers

PMID: 25797879
DOI: 10.1272/jnms.82.64

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