Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolution of DNA sequencing.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP - 1 Mar 2015

Tipu Hamid Nawaz, Shabbir Ambreen

Abstract excerpt

Sanger and coworkers introduced DNA sequencing in 1970s for the first time. It principally relied on termination of growing nucleotide chain when a dideoxythymidine triphosphate (ddTTP) was inserted in it. Detection of terminated sequences was done radiographically on Polyacrylamide Gel Electrophoresis (PAGE). Improvements that have evolved over time in original Sanger sequencing include replacement of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Mutational Analysis
Share to Epigenesis, Genetic
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Molecular Biology

Share to Molecular Diagnostic Techniques

Share to Sensitivity and Specificity

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 25772964
DOI: 03.2015/JCPSP.210215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolution of DNA sequencing.PMID 25772964Read ↗

The Journey of Genome SequencingSemantic proximity Read ↗

Next Generation DNA Sequencing: Always Allow an Opt Out.Semantic proximity Read ↗

A glimpse into past, present, and future DNA sequencing.Semantic proximity Read ↗

Advances in sequencing technology.Semantic proximity Read ↗

Next-generation sequencing: the race is on.Semantic proximity Read ↗

New DNA sequencing technologies open a promising era for cancer research and treatment.Semantic proximity Read ↗

DNA sequencing: clinical applications of new DNA sequencing technologies.Semantic proximity Read ↗

Third-generation sequencing: any future opportunities for PGT?Semantic proximity Read ↗

From early methods for DNA diagnostics to genomes and epigenomes at high resolution during four decades - a personal perspective.Semantic proximity Read ↗

Sequencing technologies and genome sequencing.Semantic proximity Read ↗

New sequencing technologies.Semantic proximity Read ↗

From the Double Helix to Precision Genomics: A Comprehensive Review of DNA and Its Transformative Role in Biomedical SciencesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.