Article
Expression of parasite genetic variation changes over the course of infection: implications of within-host dynamics for the evolution of virulence.
Proceedings. Biological sciences - 7 Apr 2015
Clerc Melanie, Ebert Dieter, Hall Matthew D
Abstract excerpt
How infectious disease agents interact with their host changes during the course of infection and can alter the expression of disease-related traits. Yet by measuring parasite life-history traits at one or few moments during infection, studies have overlooked the impact of variable parasite growth trajectories on disease evolution. Here we show that infection-age-specific estimates of host and parasite fitness...
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