Characterization of Leishmania donovani stocks by genomic DNA heterogeneity and molecular karyotype.

doi:10.1016/0035-9203(89)90377-5

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Article

Characterization of Leishmania donovani stocks by genomic DNA heterogeneity and molecular karyotype.

Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Jan 2000

Bishop R P, Akinsehinwa F

Abstract excerpt

A hypervariable deoxyribonucleic acid (DNA) probe was isolated by screening a Leishmania donovani genomic DNA library with L. donovani total DNA. The probe was used to characterize L. donovani stocks on the basis of restriction fragment length polymorphisms (RFLPs). The molecular karyotype of the...

Topics

Animals
Blotting, Southern
DNA
DNA Probes
Electrophoresis, Agar Gel
Gene Library
Genetic Variation
Isoenzymes
Karyotyping
Leishmania donovani
Nucleic Acid Hybridization
Polymorphism, Restriction Fragment Length

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