Article
Characterization of Leishmania donovani stocks by genomic DNA heterogeneity and molecular karyotype.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Jan 2000
Bishop R P, Akinsehinwa F
Abstract excerpt
A hypervariable deoxyribonucleic acid (DNA) probe was isolated by screening a Leishmania donovani genomic DNA library with L. donovani total DNA. The probe was used to characterize L. donovani stocks on the basis of restriction fragment length polymorphisms (RFLPs). The molecular karyotype of the same stocks was examined by orthogonal field alternation gel electrophoresis. On the basis of the observed RFLPs...
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