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Article

Efficacy response in CF patients treated with ivacaftor: post-hoc analysis.

Pediatric pulmonology - 1 May 2015

Konstan Michael W, Plant Barry J, Elborn J Stuart, Rodriguez Sally, Munck Anne, Ahrens Richard, Johnson Charles

Abstract excerpt

Clinical studies in patients with cystic fibrosis and G551D-CFTR showed that the group treated with ivacaftor had improved clinical outcomes. To better understand the effect of ivacaftor therapy across the distribution of individual FEV(1) responses, data from Phase 3 studies (STRIVE/ENVISION) we...

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Source

Identifiers

PMID: 25755212
DOI: 10.1002/ppul.23173

Genes

FEV
NNT
CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25755212-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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