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Insight into Shiga toxin genes encoded by <i>Escherichia coli</i> O157 from whole genome sequencing

17 Feb 2015

Abstract excerpt

The ability of Shiga toxin-producing Escherichia coli (STEC) to cause severe illness in humans is determined by multiple host factors and bacterial characteristics, including Shiga toxin (Stx) subtype. Given the link between Stx2a subtype and disease severity, we sought to identify the stx subtypes present in whole genome sequences (WGS) of 444 isolates of STEC O157. Difficulties in assembling the stx genes in...

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PMID: 25737808
DOI: 10.7717/peerj.739

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