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Intestinal Dysbiosis and Potential Consequences of Microbiome-altering Antibiotic Use in the Pathogenesis of Human Rheumatic Disease

1 Mar 2015

Abstract excerpt

The etiopathogenesis of chronic, rheumatic autoimmune disorders has been the focus of intense research since their initial literary description. Despite much scientific iteration, the current hypothesis postulates that the natural history of most such diseases is complex and multifactorial. Ultimately, it is thought that both genetic factors (including epigenetic) and environmental influences determine the fate...

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PMID: 25729039
DOI: 10.3899/jrheum.150036

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