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Article

Biological Functions of Thyroid Hormone in Placenta

16 Feb 2015

Abstract excerpt

The thyroid hormone, 3,3,5-triiodo-L-thyronine (T3), modulates several physiological processes, including cellular growth, differentiation, metabolism, inflammation and proliferation, via interactions with thyroid hormone response elements (TREs) in the regulatory regions of target genes. Infection and inflammation are critical processes in placental development and pregnancy-related diseases. In particular,...

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PMID: 25690032
DOI: 10.3390/ijms16024161

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