Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Practical considerations in the clinical application of whole‐exome sequencing

13 Feb 2015

Abstract excerpt

Despite the exciting advent of whole-exome sequencing (WES) in medical genetics practices, the optimal interpretation of results requires further actions such as reconsidering clinical information and obtaining further laboratory testing. There are no published data to guide clinicians in this process. In a retrospective study on 93 patients who underwent clinical WES, we set out to assess and resolve these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic factors in colorectal cancer
Share to Genomic variations and chromosomal abnormalities
Share to Genomics and Rare Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25678066
DOI: 10.1111/cge.12569

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Practical considerations in the clinical application of whole‐exome sequencingPMID 25678066Read ↗

Whole-exome sequencing as a diagnostic tool: current challenges and future opportunitiesSemantic proximity Read ↗

The clinical utility of whole-exome sequencing in the context of rare diseases - the changing tides of medical practice.Semantic proximity Read ↗

Whole-Exome Sequencing in the Clinic: Lessons from Six Consecutive Cases from the Clinician's PerspectiveSemantic proximity Read ↗

Genetic Diagnosis through Whole-Exome SequencingSemantic proximity Read ↗

Pitfalls of whole exome sequencing in undefined clinical conditions with a suspected genetic etiology.Semantic proximity Read ↗

Concordance between whole‐exome sequencing and clinical Sanger sequencing: implications for patient careSemantic proximity Read ↗

A toolkit for genetics providers in follow‐up of patients with non‐diagnostic exome sequencingSemantic proximity Read ↗

Clinical whole‐exome sequencing results impact medical managementSemantic proximity Read ↗

Molecular Findings Among Patients Referred for Clinical Whole-Exome SequencingSemantic proximity Read ↗

Clinical application of whole-exome sequencing across clinical indications.Semantic proximity Read ↗

Outcome of Whole Exome Sequencing for Diagnostic Odyssey Cases of an Individualized Medicine Clinic: The Mayo Clinic Experience.Semantic proximity Read ↗

The usefulness of whole-exome sequencing in routine clinical practice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.