Article
Smaller caliber renal arteries are a novel feature of uromodulin-associated kidney disease.
Kidney international - 1 Jul 2015
Prejbisz Aleksander, Sellin Lorenz, Szwench-Pietrasz Elżbieta, Woznowski Magdalena, Michałowska Ilona, Blondin Dirk, Sajnaga Dariusz, Epplen Jorg T, Litwin Mieczysław, Dekomien Gabriele, Januszewicz Magdalena, Helmchen Udo, Matuszkiewicz-Rowińska Joanna, Adamczak Marcin, Więcek Andrzej, Januszewicz Andrzej, Rump Lars C
Abstract excerpt
Hyperuricemia is very common in industrialized countries and known to promote vascular smooth muscle cell proliferation. Juvenile hyperuricemia is a hallmark of uromodulin-associated kidney disease characterized by progressive interstitial renal fibrosis leading to end-stage renal disease within decades. Here we describe a member of a Polish-German family with a history of familial background of chronic kidney...
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