Article
Tenellin acts as an iron chelator to prevent iron-generated reactive oxygen species toxicity in the entomopathogenic fungus Beauveria bassiana.
FEMS microbiology letters - 1 Jan 2015
Jirakkakul Jiraporn, Cheevadhanarak Supapon, Punya Juntira, Chutrakul Chanikul, Senachak Jittisak, Buajarern Taridaporn, Tanticharoen Morakot, Amnuaykanjanasin Alongkorn
Abstract excerpt
Iron is an essential element for life. However, the iron overload can be toxic. Here, we investigated the significant increase of tenellin and iron-tenellin complex production in ferricrocin-deficient mutants of Beauveria bassiana. Our chemical analysis indicated that the ferricrocin-deficient mutants T1, T3 and T5 nearly abolished ferricrocin production. In turn, these mutants had significant accumulation of...
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