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Article

Monocyte/macrophage-specific NADPH oxidase contributes to antimicrobial host defense in X-CGD.

Journal of clinical immunology - 1 Feb 2015

Okura Yuka, Yamada Masafumi, Kuribayashi Futoshi, Kobayashi Ichiro, Ariga Tadashi

Abstract excerpt

BACKGROUND: Chronic granulomatous disease (CGD) is a primary immunodeficiency disease that is characterized by susceptibility to bacterial and fungal infections. Various mutations in CYBB encoding the gp91(phox) subunit of the phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25666294
DOI: 10.1007/s10875-015-0138-4

Genes

CYBB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25666294-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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