Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High Discrepancy of Driver Mutations in Patients with NSCLC and Synchronous Multiple Lung Ground-Glass Nodules.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 May 2015

Wu Chunyan, Zhao Chao, Yang Yang, He Yayi, Hou Likun, Li Xuefei, Gao Guanghui, Shi Jingyun, Ren Shengxiang, Chu Haiqing, Zhou Caicun, Zhang Jun, Schmid-Bindert Gerald

Abstract excerpt

BACKGROUND: The aim of this study was to investigate the discordance rates of eight known driver mutations among multiple matched intrapulmonary ground-glass nodules (GGNs) in non-small-cell lung cancer (NSCLC) patients. METHODS: Tumors from 35 patients with multiple lesions resected, including confirmed NSCLC and at least one GGN, were analyzed for mutations in EGFR, KRAS, HER2, BRAF, and PIK3CA together with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaplastic Lymphoma Kinase
Share to Class I Phosphatidylinositol 3-Kinases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, erbB-1

Share to Genes, erbB-2

Share to Neoplasms, Multiple Primary

Share to Oncogene Proteins, Fusion

Share to Proto-Oncogene Proteins c-met

Share to Proto-Oncogene Proteins c-ret

Source

Identifiers

PMID: 25629635
DOI: 10.1097/JTO.0000000000000487

Genes

ALK
BRAF
EGFR
KRAS
ROS1
EML4
GGN
RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High Discrepancy of Driver Mutations in Patients with NSCLC and Synchronous Multiple Lung Ground-Glass Nodules.PMID 25629635Read ↗

Favorable prognosis and high discrepancy of genetic features in surgical patients with multiple primary lung cancers.Semantic proximity Read ↗

Synchronous Multiple Pulmonary Ground-Glass Nodules That Arose from Different Lesions Rather than from Multiple Metastases of a Single LesionSemantic proximity Read ↗

Clinical Features and Surgical Treatment of Synchronous Multiple Primary Lung Adenocarcinomas With Different EGFR MutationsSemantic proximity Read ↗

Discrepancy of epidermal growth factor receptor mutation in lung adenocarcinoma presenting as multiple ground-glass opacities.Semantic proximity Read ↗

Epidermal growth factor receptor mutation and pathologic-radiologic correlation between multiple lung nodules with ground-glass opacity differentiates multicentric origin from intrapulmonary spread.Semantic proximity Read ↗

Osimertinib showed efficacy on contralateral multiple ground-glass nodules after segmentectomy for lung adenocarcinoma harboring primary EGFR-T790M mutation: a case report and review of the literature.Semantic proximity Read ↗

Different EGFR gene mutations in two patients with synchronous multiple lung cancers: A case report.Semantic proximity Read ↗

Clinical Characters in Pre-invasive and Invasive Adenocarcinoma with Pulmonary Ground-glass NodulesSemantic proximity Read ↗

Molecular Testing in Multiple Synchronous Lung Adenocarcinomas: Case Report and Literature Review.Semantic proximity Read ↗

Confronting synchronous multiple primary lung cancers: Navigating the intersection of challenges and opportunities.Semantic proximity Read ↗

[Non-small Cell Lung Cancer with Metachronous Mutations of EGFR and ALK Genes: A Case Report and Literature Review].Semantic proximity Read ↗

Coexistence of atypical adenomatous hyperplasia, minimally invasive adenocarcinoma and invasive adenocarcinoma: Gene mutation analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.