Article
Comparative analysis of African swine fever virus genotypes and serogroups.
Emerging infectious diseases - 1 Feb 2015
Malogolovkin Alexander, Burmakina Galina, Titov Ilya, Sereda Alexey, Gogin Andrey, Baryshnikova Elena, Kolbasov Denis
Abstract excerpt
African swine fever virus (ASFV) causes highly lethal hemorrhagic disease among pigs, and ASFV's extreme antigenic diversity hinders vaccine development. We show that p72 ASFV phylogenetic analysis does not accurately define ASFV hemadsorption inhibition assay serogroups. Thus, conventional ASFV genotyping cannot discriminate between viruses of different virulence or predict efficacy of a specific ASFV vaccine.
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