Article
Autophagy-related prognostic signature for breast cancer.
Molecular carcinogenesis - 1 Mar 2016
Gu Yunyan, Li Pengfei, Peng Fuduan, Zhang Mengmeng, Zhang Yuanyuan, Liang Haihai, Zhao Wenyuan, Qi Lishuang, Wang Hongwei, Wang Chenguang, Guo Zheng
Abstract excerpt
Autophagy is a process that degrades intracellular constituents, such as long-lived or damaged proteins and organelles, to buffer metabolic stress under starvation conditions. Deregulation of autophagy is involved in the progression of cancer. However, the predictive value of autophagy for breast cancer prognosis remains unclear. First, based on gene expression profiling, we found that autophagy genes were...
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