Article
High content screening for modulators of cardiovascular or global developmental pathways in zebrafish.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Williams Charles H, Hong Charles C
Abstract excerpt
Major developmental pathways play critical roles in wide array of human pathologies. Chemical genomic screening allows for the discovery of novel tools not only to target known pathway interactors but also to discover new, chemically tractable targets for known pathways. The zebrafish has emerged as a useful model for developmental biology and has been well characterized. The zebrafish represents a hardy...
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