Article
Phenotyping mouse pulmonary function in vivo with the lung diffusing capacity.
Journal of visualized experiments : JoVE - 6 Jan 2015
Limjunyawong Nathachit, Fallica Jonathan, Ramakrishnan Amritha, Datta Kausik, Gabrielson Matthew, Horton Maureen, Mitzner Wayne
Abstract excerpt
The mouse is now the primary animal used to model a variety of lung diseases. To study the mechanisms that underlie such pathologies, phenotypic methods are needed that can quantify the pathologic changes. Furthermore, to provide translational relevance to the mouse models, such measurements should be tests that can easily be done in both humans and mice. Unfortunately, in the present literature few phenotypic...
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