Article
Virulence and pathogenicity of<i>Candida albicans</i>is enhanced in biofilms containing oral bacteria
2 Jan 2015
Abstract excerpt
This study examined the influence of bacteria on the virulence and pathogenicity of candidal biofilms. Mature biofilms (Candida albicans-only, bacteria-only, C. albicans with bacteria) were generated on acrylic and either analysed directly, or used to infect a reconstituted human oral epithelium (RHOE). Analyses included Candida hyphae enumeration and assessment of Candida virulence gene expression. Lactate...
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