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Article

OPA1-related auditory neuropathy: site of lesion and outcome of cochlear implantation.

Brain : a journal of neurology - 1 Mar 2015

Santarelli Rosamaria, Rossi Roberta, Scimemi Pietro, Cama Elona, Valentino Maria Lucia, La Morgia Chiara, Caporali Leonardo, Liguori Rocco, Magnavita Vincenzo, Monteleone Anna, Biscaro Ariella, Arslan Edoardo, Carelli Valerio

Abstract excerpt

Hearing impairment is the second most prevalent clinical feature after optic atrophy in dominant optic atrophy associated with mutations in the OPA1 gene. In this study we characterized the hearing dysfunction in OPA1-linked disorders and provided effective rehabilitative options to improve speech perception. We studied two groups of OPA1 subjects, one comprising 11 patients (seven males; age range 13-79 years)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cochlear Implantation

Share to Evoked Potentials, Auditory, Brain Stem

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Share to Magnetic Resonance Imaging

Share to Otoacoustic Emissions, Spontaneous

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Source

Open in PubMed Open full text

Identifiers

PMID: 25564500
DOI: 10.1093/brain/awu378
PMCID: PMC4339771

Genes

OPA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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