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Article

Dynamics of MDR Enterobacter cloacae outbreaks in a neonatal unit in Nepal: insights using wider sampling frames and next-generation sequencing.

The Journal of antimicrobial chemotherapy - 1 Apr 2015

Stoesser N, Sheppard A E, Shakya M, Sthapit B, Thorson S, Giess A, Kelly D, Pollard A J, Peto T E A, Walker A S, Crook D W

Abstract excerpt

OBJECTIVES: There are limited data on Enterobacter cloacae outbreaks and fewer describing these in association with NDM-1. With whole-genome sequencing, we tested the hypothesis that a cluster of 16 E. cloacae bacteraemia cases in a Nepali neonatal unit represented a single clonal outbreak, using a wider set of epidemiologically unrelated clinical E. cloacae isolates for comparison. METHODS: Forty-three isolates...

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Identifiers

PMID: 25558071
DOI: 10.1093/jac/dku521
PMCID: PMC4356206

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