Article
Clinical and prognostic importance of chromosomal abnormalities, Y chromosome microdeletions, and CFTR gene mutations in individuals with azoospermia or severe oligospermia.
Turkish journal of medical sciences - 1 Jan 2014
Ocak Zeynep, Üyetüork Uğur, Dinçer Muhammet Murat
Abstract excerpt
AIM: To illustrate the importance of genetic screening in the assessment of fertility and the correct diagnosis in patients with azoospermia or severe oligospermia. MATERIALS AND METHODS: This study examined 500 patients with reproductive failure, having fewer than 5 million sperm/mL detected in at least 2 consecutive spermiograms, who presented at a medical genetics polyclinic between 2008 and 2012. Metaphase...
Topics
- Azoospermia
- Chromosome Aberrations
- Chromosome Deletion
- Chromosomes, Human, Y
- Cystic Fibrosis Transmembrane Conductance Regulator
- Genetic Testing
- Heterozygote
- Humans
- Infertility, Male
- Male
- Mutation
- Oligospermia
- Prognosis
- Turkey
- Vas Deferens