Article
Study of Mycobacterium tuberculosis complex genotypic diversity in Malaysia reveals a predominance of ancestral East-African-Indian lineage with a Malaysia-specific signature.
PloS one - 1 Jan 2014
Ismail Fazli, Couvin David, Farakhin Izzah, Abdul Rahman Zaidah, Rastogi Nalin, Suraiya Siti
Abstract excerpt
BACKGROUND: Tuberculosis (TB) still constitutes a major public health problem in Malaysia. The identification and genotyping based characterization of Mycobacterium tuberculosis complex (MTBC) isolates causing the disease is important to determine the effectiveness of the control and surveillance programs. OBJECTIVES: This study intended a first assessment of spoligotyping-based MTBC genotypic diversity in...
Topics
- Asia
- Bacterial Typing Techniques
- Genetic Variation
- Genotype
- Humans
- Malaysia
- Mycobacterium tuberculosis
- Phylogeography
- Tuberculosis