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Article

Implementation of a companion diagnostic in the clinical laboratory: the BRAF example in melanoma.

Clinica chimica acta; international journal of clinical chemistry - 15 Jan 2015

Mancini Irene, Pinzani Pamela, Simi Lisa, Brandslund Ivan, Vermeersch Pieter, Di Resta Chiara, Schwab Matthias, Marc Janja, van Schaik Ron, Pazzagli Mario

Abstract excerpt

A companion diagnostic test provides information that is essential for the safe and effective use of a corresponding therapeutic product as indicated in the drug instructions. The implementation of a companion diagnostic follows the rules of a molecular test for somatic mutations in a routine clinical laboratory environment and needs guidance on practical aspects, including the choice of the proper analytical...

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Source

Identifiers

PMID: 25454717
DOI: 10.1016/j.cca.2014.10.020

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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