Article
Bovine herpesvirus-1: evaluation of genetic diversity of subtypes derived from field strains of varied clinical syndromes and their relationship to vaccine strains.
Vaccine - 15 Jan 2015
Fulton R W, d'Offay J M, Eberle R, Moeller R B, Campen H Van, O'Toole D, Chase C, Miller M M, Sprowls R, Nydam D V
Abstract excerpt
Bovine herpesvirus-1 (BoHV-1) causes significant disease in cattle. Control programs in North America incorporate vaccination with modified live viral (MLV) or killed (KV) vaccine. BoHV-1 strains are isolated from diseased animals or fetuses after vaccination. There are markers for differentiating MLV from field strains using whole-genome sequencing and analysis identifying single nucleotide polymorphisms (SNPs)....
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