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Article

Prevalence and clinical correlates of familial hypercholesterolemia founder mutations in the general population.

Atherosclerosis - 1 Jan 2015

Lahtinen Annukka M, Havulinna Aki S, Jula Antti, Salomaa Veikko, Kontula Kimmo

Abstract excerpt

OBJECTIVE: This study aimed to investigate the exact prevalence of familial hypercholesterolemia (FH) in the general population, taking advantage of the fact that five low-density lipoprotein receptor (LDLR) founder mutations account for 78% of FH cases in Finland. METHODS: Five LDLR founder mutations, FH-North Karelia, FH-Helsinki, FH-Pogosta, FH-Turku, and FH-Pori, were genotyped and serum lipid levels were...

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Identifiers

PMID: 25437892
DOI: 10.1016/j.atherosclerosis.2014.11.015

Genes

LDLR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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