Article
Novel ITGB6 mutation in autosomal recessive amelogenesis imperfecta.
Oral diseases - 1 May 2015
Seymen F, Lee K-E, Koruyucu M, Gencay K, Bayram M, Tuna E B, Lee Z H, Kim J-W
Abstract excerpt
OBJECTIVE: Hereditary defects in tooth enamel formation, amelogenesis imperfecta (AI), can be non-syndromic or syndromic phenotype. Integrins are signaling proteins that mediate cell-cell and cell-extracellular matrix communication, and their involvement in tooth development is well known. The purposes of this study were to identify genetic cause of an AI family and molecular pathogenesis underlying defective...
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