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The Multiple Roles of sGP in Ebola Pathogenesis

29 Oct 2014

Abstract excerpt

Ebola causes severe hemorrhagic fever in humans and nonhuman primates, and there are currently no approved therapeutic countermeasures. The virulence of Ebola virus (EBOV) may be partially attributed to the secreted glycoprotein (sGP), which is the main product transcribed from its GP gene. sGP is secreted from infected cells and can be readily detected in the serum of EBOV-infected hosts. This review summarizes...

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PMID: 25354393
DOI: 10.1089/vim.2014.0068

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