Article
Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse.
PLoS genetics - 1 Oct 2014
DiTommaso Tia, Jones Lynelle K, Cottle Denny L, Gerdin Anna-Karin, Vancollie Valerie E, Watt Fiona M, Ramirez-Solis Ramiro, Bradley Allan, Steel Karen P, Sundberg John P, White Jacqueline K, Smyth Ian M
Abstract excerpt
The skin is a highly regenerative organ which plays critical roles in protecting the body and sensing its environment. Consequently, morbidity and mortality associated with skin defects represent a significant health issue. To identify genes important in skin development and homeostasis, we have applied a high throughput, multi-parameter phenotype screen to the conditional targeted mutant mice generated by the...
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