Article
Identification of Rare, Single-Nucleotide Mutations in NDE1 and Their Contributions to Schizophrenia Susceptibility.
Schizophrenia bulletin - 1 May 2015
Kimura Hiroki, Tsuboi Daisuke, Wang Chenyao, Kushima Itaru, Koide Takayoshi, Ikeda Masashi, Iwayama Yoshimi, Toyota Tomoko, Yamamoto Noriko, Kunimoto Shohko, Nakamura Yukako, Yoshimi Akira, Banno Masahiro, Xing Jingrui, Takasaki Yuto, Yoshida Mami, Aleksic Branko, Uno Yota, Okada Takashi, Iidaka Tetsuya, Inada Toshiya, Suzuki Michio, Ujike Hiroshi, Kunugi Hiroshi, Kato Tadafumi, Yoshikawa Takeo, Iwata Nakao, Kaibuchi Kozo, Ozaki Norio
Abstract excerpt
BACKGROUND: Nuclear distribution E homolog 1 (NDE1), located within chromosome 16p13.11, plays an essential role in microtubule organization, mitosis, and neuronal migration and has been suggested by several studies of rare copy number variants to be a promising schizophrenia (SCZ) candidate gene. Recently, increasing attention has been paid to rare single-nucleotide variants (SNVs) discovered by deep sequencing...
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