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Down regulation of Thrombospondin2 predicts poor prognosis in patients with gastric cancer

28 Sept 2014

Abstract excerpt

BACKGROUND: Thrombospondins (THBSs) are a family of multidomain and secreted matricellular Ca(2+)-binding glycoproteins which has at least five members encoded by independent genes. As a THBSs family member, Thrombospondin2 (THBS2) has been reported to regulate angiogenesis. Nevertheless, the functions and clinical significance of THBS2 still remains unclear in gastric cancer. METHODS: The mRNA and protein...

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PMID: 25262009
DOI: 10.1186/1476-4598-13-225

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