Article
Mutation screening of HOXA7 and HOXA9 genes in Chinese women with Müllerian duct abnormalities.
Reproductive biomedicine online - 1 Nov 2014
Chen Xinxia, Mu Yulan, Li Chunyan, Li Guangyu, Zhao Hui, Qin Yingying, Chen Zi-Jiang
Abstract excerpt
HOXA genes in groups 7-13 have been proven to play a role in determining positional identity along the genitalia axis. The aim of the present study was to explore the relationship between HOXA7 and HOXA9 mutations and Müllerian duct abnormalities (MDA). One hundred and ninety-two Chinese patients with MDA abnormalities and 192 healthy controls were recruited. All coding regions of HOXA7 and HOXA9 were amplified...
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