Article
The role of enterovirus 71 and coxsackievirus A strains in a large outbreak of hand, foot, and mouth disease in 2012 in Changsha, China.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Nov 2014
Chen Jing-Fang, Zhang Ru-Sheng, Ou Xin-Hua, Chen Fa-Ming, Sun Bian-Cheng
Abstract excerpt
BACKGROUND: During 2012, Changsha experienced a large outbreak of hand, foot, and mouth disease (HFMD), resulting in 25,438 cases, including 42 severe cases and eight deaths. METHODS: Seven hundred and forty-six clinical specimens were collected from hospital-based surveillance for HFMD in 2012. The detection and genotyping of enterovirus were performed by real-time RT-PCR and sequencing of the VP1 regions;...
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