Article
Common variation near ROBO2 is associated with expressive vocabulary in infancy.
Nature communications - 16 Sept 2014
St Pourcain Beate, Cents Rolieke A M, Whitehouse Andrew J O, Haworth Claire M A, Davis Oliver S P, O'Reilly Paul F, Roulstone Susan, Wren Yvonne, Ang Qi W, Velders Fleur P, Evans David M, Kemp John P, Warrington Nicole M, Miller Laura, Timpson Nicholas J, Ring Susan M, Verhulst Frank C, Hofman Albert, Rivadeneira Fernando, Meaburn Emma L, Price Thomas S, Dale Philip S, Pillas Demetris, Yliherva Anneli, Rodriguez Alina, Golding Jean, Jaddoe Vincent W V, Jarvelin Marjo-Riitta, Plomin Robert, Pennell Craig E, Tiemeier Henning, Davey Smith George
Abstract excerpt
Twin studies suggest that expressive vocabulary at ~24 months is modestly heritable. However, the genes influencing this early linguistic phenotype are unknown. Here we conduct a genome-wide screen and follow-up study of expressive vocabulary in toddlers of European descent from up to four studies of the EArly Genetics and Lifecourse Epidemiology consortium, analysing an early (15-18 months, 'one-word stage',...
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