Article
Role of surface protective antigen A in the pathogenesis of Erysipelothrix rhusiopathiae strain C43065.
Journal of microbiology and biotechnology - 1 Feb 2015
Borrathybay Entomack, Gong Feng-Juan, Zhang Lei, Nazierbieke Wulumuhan
Abstract excerpt
To clarify the role of surface protective antigen A (SpaA) in the pathogenesis of Erysipelothrix rhusiopathiae C43065 (serotype 2), the spaA deletion mutant of E. rhusiopathiae ΔspaA was constructed by homologous recombination. The virulence of the ΔspaA mutant decreased more than 76-fold compared with that of the wild-type strain C43065 in mice. The mutant strain was sensitive to the bactericidal action of swine...
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